Yazar "Arıkan, Muzaffer" için listeleme
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Axillary microbiota is associated with cognitive impairment in parkinson's disease patients
Arıkan, Muzaffer; Yıldız, Zeynep; Kahraman Demir, Tuğçe; Helvacı Yılmaz, Nesrin; Şen, Aysu; Hanoğlu, Lütfü; Yıldırım, Süleyman (American Society for Microbiology, 2022)Cognitive impairment (CI) is among the most common non-motor symptoms of Parkinson's disease (PD), with a substantially negative impact on patient management and outcome. The development and progression of CI exhibits high ... -
Comparison of S gene mutations in patients with occult and chronic hepatitis B virus infection
Çakal, Bülent; Çavuş, Bilger; Atasoy, Alp; Altunok, Damla; Poda, Mehveş; Bulakçı, Mesut; Gülluoğlu, Mine; Demirci, Mehmet; Türker Şener, Leyla; Arslan, Aslı Berru; Arıkan, Muzaffer; Akyüz, Filiz (Elsevier B.V., 2022)Background and aim: This study aimed to detect mutations in the HBV S gene and evaluate their relationship to occult hepatitis B virus (HBV) infection (OBI). Methods: The study included 32 patients with negative serum HBsAg ... -
Genomic analysis reveals the biotechnological and industrial potential of levan producing halophilic extremophile, Halomonas smyrnensis AAD6T
Diken, Elif; Özer, Tuğba; Arıkan, Muzaffer; Emrence, Zeliha; Toksoy Öner, Ebru; Üstek, Duran; Arğa, Kazım Yalçın (Springer International Publishing, 2015)Halomonas smyrnensis AAD6T is a gram negative, aerobic, and moderately halophilic bacterium, and is known to produce high levels of levan with many potential uses in foods, feeds, cosmetics, pharmaceutical and chemical ... -
An in silico investigation of anticancer peptide candidates in fermented food microbiomes
Arıkan, Muzaffer (Istanbul University, 2023)Objective: Cancer is a leading cause of death worldwide, requires development of new effective, specific, and safe strategies that do not carry the disadvantages of traditional cancer treatment approaches. Hence, this study ... -
Integrated multi-omics analyses of microbial communities: A review of the current state and future directions
Arıkan, Muzaffer; Muth, Thilo (Royal Society of Chemistry, 2023)Integrated multi-omics analyses of microbiomes have become increasingly common in recent years as the emerging omics technologies provide an unprecedented opportunity to better understand the structural and functional ... -
Metaproteogenomic analysis of saliva samples from Parkinson's disease patients with cognitive impairment
Arıkan, Muzaffer; Kahraman Demir, Tuğçe; Yıldız, Zeynep; Nalbantoğlu, Özkan Ufuk; Korkmaz, Nur Damla; Helvacı Yılmaz, Nesrin; Şen, Aysu; Özcan, Mutlu; Muth, Thilo; Hanoğlu, Lütfü; Yıldırım, Süleyman (Nature Portfolio, 2023)Cognitive impairment (CI) is very common in patients with Parkinson's Disease (PD) and progressively develops on a spectrum from mild cognitive impairment (PD-MCI) to full dementia (PDD). Identification of PD patients at ... -
Microbial composition of Kombucha determined using amplicon sequencing and shotgun metagenomics
Arıkan, Muzaffer; Mitchell, Alex L.; Finn, Robert D.; Gürel, Filiz (Wiley, 2020)Kombucha, a fermented tea generated from the co-culture of yeasts and bacteria, has gained worldwide popularity in recent years due to its potential benefits to human health. As a result, many studies have attempted to ... -
Parkinson hastalığı demansı ile bağırsak mikrobiyotasındaki akkermansia genomik çeşitliliği arasındaki ilişkinin incelenmesi
Arıkan, Muzaffer; Kahraman Demir, Tuğçe; Yıldız, Zeynep; Helvacı Yılmaz, Nesrin; Şen, Aysu; Hanoğlu, Lütfü; Yıldırım, Süleyman (Ankara Mikrobiyoloji Derneği, 2024)Parkinson hastalığında (PH), genellikle sağlıkla ilişkilendirilen bir bakteri cinsi olan Akkermansia’nın bağırsak mikrobiyotasında artış gösterdiği bilinse de bu artışın nedeni tam olarak anlaşılamamıştır. Bu çalışmada ... -
Stratification of the gut microbiota composition landscape across the alzheimer's disease continuum in a Turkish cohort
Yıldırım, Süleyman; Nalbantoğlu, Özkan Ufuk; Bayraktar, Abdulahad; Ercan, Fatma Betül; Gündoğdu, Aycan; Velioğlu, Halil Aziz; Göl, Mehmet Fatih; Ekinci Soylu, Ayten; Koç, Fatma; Aslan Gülpınar, Ezgi; Soğukkanlı Kadak, Kübra; Arıkan, Muzaffer; Mardinoğlu, Adil; Koçak, Mehmet; Köseoğlu, Emel; Hanoğlu, Lütfü (American Society for Microbiology, 2022)Alzheimer's disease (AD) is a heterogeneous disorder that spans a continuum with multiple phases, including preclinical, mild cognitive impairment, and dementia. Unlike for most other chronic diseases, human studies reporting ... -
Türkiye popülasyonunda HLA-DQ polimorfizmlerinin Hepatit B virüs enfeksiyonu ile ilişkisi
Çakal, Bülent; Arıkan, Muzaffer; Atasoy, Alp; Çavuş, Bilger; Poda, Mehveş; Bulakçı, Mesut; Güllüoğlu, Mine; Demirci, Mehmet; Akyüz, Filiz (İstanbul Üniversitesi, 2022)Amaç Konak genetik faktörleri hepatit B virüs (HBV) enfeksiyonunun doğal seyri ve HBV ilişkili karaciğer hastalıklarının gelişme riski ile progresyonu üzerinde etkili olabilmektedir. Bu çalışmada HLA-DQ gen rs9272105, ... -
Water as source of Francisella tularensis infection in humans, Turkey
Kılıç, Selçuk Sirri; Birdsell, Dawn; Karagöz, Alper; Çelebi, Bekir; Bakkaloǧlu, Zekiye; Arıkan, Muzaffer; Sahl, Jason; Mitchell, Cedar; Rivera, Andrew; Maltinsky, Sara; Keim, Paul; Üstek, Duran; Durmaz, Rıza; Wagner, David (Centers Disease Control, 2015)Francisella tularensis DNA extractions and isolates from the environment and humans were genetically characterized to elucidate environmental sources that cause human tularemia in Turkey. Extensive genetic diversity ...